GABA is not the same as gabapentin. GABA (gamma-aminobutyric acid) is an amino acid supplement; gabapentin is a prescription medication.
The differences between GABA and gabapentin lie in their mechanisms of action in the brain – GABA targets GABA receptors whereas gabapentin
Gabapentin Mechanism of action. Gabapentin does not act directly on GABA receptors in spite of their close structural resemblance to GABA. They may, however, modify the synaptic or nonsynaptic release of GABA. An increase in brain GABA concentration is observed in patients receiving gabapentin.
Gabapentin is structurally related to the neurotransmitter GABA (gamma-aminobutyric acid), but it does not modify GABA A or GABA B radioligand binding, it is not converted metabolically into GABA or a GABA agonist, and it is not an inhibitor of GABA uptake or degradation. In radioligand binding assays at concentrations up to 100 M, gabapentin
GABA is not the same as gabapentin. GABA (gamma-aminobutyric acid) is an amino acid supplement and neurotransmitter; gabapentin is a
What is Gabapentin and What are the Uses of Gabapentin for Cats? Gabapentin is a structural analog of gamma-aminobutyrate (GABA). GABA is an inhibitory neurotransmitter. The mechanism of action of Gabapentin is however not completely understood. It was designed to mimic the GABAs mechanism.
In summary, GABA is a natural inhibitory neurotransmitter, while gabapentin is a medication that can mimic the effect of GABA. Both GABA and gabapentin play a
Gabapentin is structurally related to the neurotransmitter GABA (gamma GABA agonist, and it is not an inhibitor of GABA uptake or degradation. The
Gabapentin is structurally related to the neurotransmitter GABA (gamma GABA agonist, and it is not an inhibitor of GABA uptake or degradation. The
Comments
This story is great fun; it's sexy too. I especially enjoyed the heroine/narrator's personality, including her fairly strong—but decidedly quirky—ethical principles. I do feel sorry for her uncle, though. He got left out of the action entirely. Perhaps there will be a Part 3? Fine with me, if so.
Not much good news. Went to my neuropathist on Wednesday for a series of tests. 'Yes', I have nerve damage and 'no', the doctor looking at the results couldn't understand why. Essentially, they ran an escalating electric current from various spots on my lower leg and foot to toes to see how I responded. I highly recommend this as a means of torture.
On the downside, I am becoming resistant to my pain medication, so life sucks coming and going. My psychiatrist upped my Gabapentin from 300 Mg to 400 Mg [3x a day] and it isn't helping. Woot? I'd kill for a decent night's sleep.
Thank you for asking. I really wish I had better news.
James aka FinalStand
On the beneficial side, I know where I want to take Chapter 5 in this tale. I have much of it mapped out in my mind.
They travel to the mainland in pursuit of the Atlanteans ... which completes the 13th Circle of the Black Witches Coven (whoops!) ~ giving the descendants of the other 7 the power they have been long denied. There is still the government task force on the serial killings to deal with plus the on-going conflict with the White Coven. The main mystery remains ~ what was an Atlantean doing breeding with an Abenaki and teaching at least one half-breed offspring magic over 400 years ago ... and why would a normally amoral Altantean 'noble' be interested in said half-breed today?
God - sometimes I really wish I had a clone ... or two.
James aka FinalStand
As for everyone else ... life keeps adding on the 'happy' {sarcasm}.
My neurologist decided to prescribe a more powerful tool to manage the pain in my feet. So, he gave me a foot cream. What wasn't obvious was the non-prescribed 'side effects' of the foot cream which included ... (sigh) ...
Well, as my feet have been hurting like sons-a-bitches, I was slathering that cream on three and four times a day. It had minimal positive effect which was leagues ahead of the pain I was going through. Besides, it was foot cream. What was the worse that could happen?
Baclofen (2%) ~ [Lightheadedness or fainting, trouble seeing, severe tiredness, weakness],
Cyclobenzaprine (2%) ~ [Anxiety, restlessness, seeing or hearing things that are not there, severe drowsiness, fainting, or confusion],
Diclofenac (3%) ~ [Sudden or severe headache, or problems with vision, speech, or walking],
Gabapentin (6%) ~ [Behavior problems, aggression, restlessness, trouble concentrating, moodiness (especially in children), problems with coordination, shakiness, unsteadiness, unusual moods, or behaviors, thoughts of hurting yourself, feeling depressed, dizziness, drowsiness, sleepiness, tiredness],
Lidocaine (2%) ~ [which, somewhat stunningly, isn't trying to fuck with my head]
So I've been staggering around in a semi-lucid state for the past several days, unable to figure out why I couldn't do much, if any, writing. It took me complaining to my wife to provide some clarity.
I repeat - it is freaking foot cream!
I've stopped with the foot-crack and am back to dealing with the pain. Hopefully I'll be back to writing soon too.
James aka FinalStand
I often think about how I'd love to read a story on here in the BDSM category where the sub was chronically ill and how that'd change the play. I'd love to read the steps the Dom would take to make BDSM accessible for the sub while still being mindful of her symptoms and limitations, which can be a broad, varied, long, and constantly changing list. It'd be fascinating to read the tricks and work arounds the Dom would use to still accommodate the sub's desires while constantly having to keep an eye on her health and limits considering that the chronically ill often push themselves harder than they should in every day life and pay for it later with pain, exhaustion, and/or an increase in symptoms of their illness. I've considered pitching this idea one of my favorite authors here but she's in the middle of a long series right now. Anyway, this story is the closest I've come to finding something like that here and it was lovely. Usually what I come across that includes disability, especially in Romance, are stories where a person is either blind or deaf, or a spouse or parent finding love again after cancer has taken their spouse/child. While those are great, they don't necessarily encompass the often shifting landscape of living with many neurological or rare diseases or even of living with cancer (rather than being the widow/widower). Representation matters and it was great to come across a story where the person has a symptom like mine. Thank you.