Additive anticholinergic adverse effects may occur. tetrabenazine. tetrabenazine and promethazine both decrease QTc interval. Avoid or Use Alternate Drug. thioridazine. promethazine and thioridazine both increase QTc interval. Avoid or Use Alternate Drug. tranylcypromine. tranylcypromine increases effects of promethazine by Other (see comment).
Use Caution/Monitor. promethazine. promethazine and azithromycin both increase QTc interval. Use Caution/Monitor. propafenone. azithromycin increases toxicity
On average the patient's QTc interval changed between promethazine, the promethazine being added for its anticholinergic
The optimal time to measure QTc is when the QTc-prolonging medication is at steady state. Promethazine (Phenergan). Trazodone (Desyrel). Clozapine (Clozaril).
promethazine. sertraline and promethazine both decrease QTc interval. Use Caution/Monitor. propranolol.
Promethazine and Treatment Refractory Agitation in Clonidine Toxicity QTc and long PR in electrocardiogram as well as severe agitation with gloss
promethazine. buprenorphine and promethazine both decrease QTc interval. Avoid or Use Alternate Drug. propafenone.
The safest antiemeitcs from a QTc prolongation perspective are metoclopramide, prochlorperazine, and promethazine. Trimethobenzamide is also an
Promethazine: (Major) Concomitant use of azithromycin and promethazine increases the risk of QT/QTc prolongation and torsade de pointes (TdP). Avoid
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